We commissioned an independent in-home testing platform used by leading global consumer brands to run a 7-night study with 100 adults in their own homes, in their own beds, living their real lives.
Conducted in real homes, with real sleep conditions.
NightWise Sleep
A 3-Phase system built to help your night hold together, even when it breaks in the middle of the night.
See Where to Buy →Because they don’t stay with you through the night.
You fall asleep fine.
Then 2 AM.
Wide awake.
And by morning,
it feels like you never really slept at all.
That’s where your night breaks.
Built for sleep that breaks
in the middle of the night.
Available now at select retailers.
Formulated with clinically studied, non-habit-forming ingredients. Drug-free and available without a prescription.
Most sleep supplements release everything at bedtime, then fade. NightWise was designed to keep working later in the night.
Your body doesn’t need support all at once. It needs it at the moments your night is most likely to break.
NightWise® is built on NightWise’s patented 3-Phase Intelligent Release Technology®, designed to deliver sleep support at bedtime and again hours later, when standard supplements have already worn off.
Naturally derived ingredients selected to support relaxation and sleep.*
NightWise is built on NightWise’s patented 3-Phase Intelligent Release Technology®, designed to support sleep at both the beginning of the night and hours later.
Most products start your night. They don’t carry it through.
What this means: your night holds together. And your sleep finally works.
A complete three-phase sleep stack for adults with disrupted sleep. Falls asleep, stays asleep, wakes restored. The foundation of the IRT® platform.
NightWise commissioned an independent in-home user testing platform used by leading global consumer brands to run a 7-night study with 100 participants in their own homes, with their real sleep problems.
Most sleep products improve one part of the night. NightWise improves the entire night.
Typical sleep solutions improve onset for ~40–55% of users and rarely support the full night.
Study design: Independent in-home user test · n=100 · 7 nights · Results may vary individually.
Two minutes. We will guide you to the right NightWise formula.
Not sure NightWise® Sleep is right for you? Answer four questions.
Sleep is not one continuous state. It unfolds in phases. NightWise® supports each phase with Intelligent Release Technology®, delivering the right ingredients at the right time across the full night.
Precisely timed support across the full night.
What people experience when their sleep finally holds through the night.
NightWise uses trusted, clinically studied ingredients. What makes it different is when they’re delivered.
The IRT® platform is the only patented multi-phase bead delivery system in the sleep supplement category.
No sedatives.
No synthetic hormones.
No habit-forming ingredients.
A patented three-phase system
designed to support sleep
from lights out to wake up.
Drug-free.
Available without a prescription.
Three issued U.S. patents. Independently studied in real-world conditions. A delivery system built around timing, not just ingredients.
Your night doesn’t hold all at once. It unfolds over time.
Most sleep products are built for the beginning of the night. NightWise is built to support what happens after.
NightWise is built on a patented delivery system designed to release support across the full night.
A different way to support sleep. One that stays with you beyond the first hours of the night.
A 3-Phase Intelligent Release system. Each phase is released at a different point in the night, helping your sleep hold together from start to finish.
What’s happening in your body at night, and why it doesn’t always feel the way it should.
You can fall asleep and still wake up feeling off. You can sleep for hours and still not feel restored.
Night Shift is where we break down what’s actually happening across the night, and why sleep doesn’t always hold the way you expect it to.
Some products make you drowsy. That’s not the same as real sleep.
It helps you fall asleep. But it doesn’t support the rest of your night.
5 min readThe most important part of your night is the part most people lose.
6 min readFalling asleep is only the beginning. Holding sleep is where it gets difficult.
6 min readYour internal rhythm is constantly adjusting. When it’s off, your night changes.
7 min readHormonal shifts don’t just affect how you fall asleep. They change how your night behaves.
8 min readInterruptions don’t just wake you up. They break the structure of your night.
7 min readReal-world results from a 7-night in-home study.
View Study →Editorial Standard NightWise education articles are written by our team and reviewed by independent medical editors before publication. We publish to inform, not to sell. These statements have not been evaluated by the Food and Drug Administration.
NightWise® is launching at retail in August 2026. Find the right retailer for you, online and in stores.
Answer four quick questions. We’ll map where your night breaks, and match you with the NightWise formula built for that moment.
Your night doesn’t fall apart all at once. We’re identifying exactly where it breaks.