We commissioned an independent in-home testing platform used by leading global consumer brands to run a 7-night study with 100 adults in their own homes, in their own beds, living their real lives.

Conducted in real homes, with real sleep conditions. NightWise®, Real Sleep. Real Life.

3 U.S. Patents  ·  Independently Studied  ·  NightWise® Patented Intelligent Release Technology®
THIS IS REAL SLEEP.

Show up sharp.

Because your night didn’t break at 3 AM.

Real Sleep. Real Life.

THIS IS REAL SLEEP.

Be there when it matters.

Because your sleep held through the night.

Real Sleep. Real Life.

THIS IS REAL SLEEP.

Own your day.

You didn’t just sleep. You made it through the night.

Real Sleep. Real Life.

THIS IS REAL SLEEP.

Feel like yourself again.

Because your nights finally hold steady.

Real Sleep. Real Life.

THIS IS REAL SLEEP.

Sleep through the night.

Because your sleep finally holds.

Real Sleep. Real Life.

Find Your Formula How It Works
3 U.S. Patents
Independently Studied
Non-Habit Forming
🏭
GMP Manufactured
The Problem

Your sleep didn’t fail at bedtime. It broke in the middle of the night.

You fall asleep. Then something changes.
A few hours into the night, your body begins to shift.
That’s when sleep becomes easier to break.

MOST VULNERABLE WINDOW BEDTIME Middle of the Night 2–4 AM MORNING

This is where sleep is most vulnerable.

And where recovery is most often lost.

Sleep isn’t a single moment.
It’s something your body has to complete.

Most solutions don’t stay with you through the night.

You’ve felt this before.
You wake up in the middle of the night.
And the night never really recovers.

Pattern 01
Can't fall asleep.
Your mind won't quiet. Too much melatonin, too fast. Your body can't use it.
Pattern 02
Fall asleep. Wake at 3 AM.
The supplement wore off. Nothing left for the second half of the night.
Pattern 03
Sleep through. Wake exhausted.
The restorative phases were disrupted. A standard supplement was never designed to help.
Why Solutions Fall Short

Built for one moment. Not the full night.

Most sleep products work fast. Then they fade. They start the night. They don’t carry it through.

Most sleep aids were built for sedation.

Sedation isn’t real sleep.

Most Single-Release Sleep Supplements
WORN OFF Bedtime Middle of the Night Morning
Peaks fast. Wears off too early. Nothing left for the second half of the night.

After a while, you stop expecting anything to work.

Sleep doesn’t break at bedtime.
It breaks in the middle of the night.

So the solution has to work through it.

Because real sleep only works when your night holds together.

The Breakthrough

Built for the full night.

NightWise works differently.

It doesn’t just start your sleep.
It stays with you through it.

Designed to support your body across the night.
Not just the moment you fall asleep. But the hours that follow, and the recovery that completes it.

Built on NightWise’s patented Intelligent Release Technology®, a delivery system that follows the night, not just bedtime.

Phase 1
Bedtime
Sleep onset
Phase 2: Controlled Hold
Hours 1–2
Support is held back until your body needs it most.
Phase 3
Middle of Night
Deep restore
1
Phase 1 · 0–30 min
Fall Asleep
Gently helps your body settle into sleep.
2
Phase 2 · 1–2 hrs
Stay Asleep
Holds support so your sleep doesn’t drop off too early.
3
Phase 3 · Hours 2–8
Restore Deeply
Sustains support through the middle of the night, when recovery matters most.
Intelligent Release Technology® Delivery Profile

Timed to support your night, start to finish.

CONTROLLED HOLD PHASE 1 PHASE 3
Bedtime Middle of the Night Morning
Phase 1, Sleep Onset
Phase 2: Controlled Hold
Phase 3, Deep Restore

This is how real sleep gets supported across the night.

3-Phase Intelligent Release Technology® · Patent Portfolio

Protected by three issued U.S. patents covering timed-release sleep delivery. This system is uniquely NightWise.

Phase 1 Phase 2 Phase 3
U.S. Patent 11,351,150
Covers a multilayer particle that provides time-sequence delivery of sleep promoting and sleep quality agents.
U.S. Patent 11,890,271
Covers a capsule delivery system that provides time-sequence delivery of sleep promoting and sleep quality agents.
U.S. Patent 12,419,860
Covers a multi-bead composition that provides time-sequence delivery of sleep promoting and sleep quality agents.

Three issued U.S. patents. See the full patent portfolio →

This is how your night holds together.
And how real sleep finally works.

Not sure where to start?

You don’t have to guess anymore.

Two minutes. Four questions. Built around how your sleep actually breaks down.

The Evidence

When sleep works, you feel it.
Here’s what people actually experienced.

Independent results.
Real people. Real nights.

We commissioned an independent in-home testing platform to run a 7-night study with 100 adults in their own homes, in their own beds, with their real sleep problems.

No lab. No controlled environment. The kind of test that matters.

Study design: Independent in-home user test · n=100 · 7 nights · Results may vary individually.

75%
reported improved sleep quality
69%
fell asleep faster
70%
slept longer through the night
69%
fewer nighttime awakenings
62%
woke alert and refreshed
NightWise® Sleep ,  a night where sleep finally stays
NightWise® Sleep

For nights that don’t hold.

Sleep doesn’t break when you fall asleep.
It breaks in the middle of the night.

NightWise is designed to stay with you. So your night holds together.

  • One system. Built to carry your night from start to finish.

Formulated with clinically studied ingredients. Drug-free. Built for real sleep.

NightWise Sleep

NightWise Sleep bottle

A 3-Phase system built to help your night hold together, even when it breaks in the middle of the night.

See Where to Buy →
NightWise® Sleep · Everyday Sleep Support

Every sleep supplement
was built to help you fall asleep.

None of them
were built to keep you there.

Because they don’t stay with you through the night.

You fall asleep fine.

Then 2 AM.
Wide awake.

And by morning,
it feels like you never really slept at all.

That’s where your night breaks.

Built for sleep that breaks
in the middle of the night.

Available now at select retailers.

Formulated with clinically studied, non-habit-forming ingredients. Drug-free and available without a prescription.

See Where to Buy → Available now at select retailers · 28 capsules · 28 doses · 1 per night
Sleep doesn’t break at bedtime.
It breaks in the middle of the night.
🌙
Most supplements solve bedtime
The real problem is 2–3 AM
⚠️
That’s where your night breaks. And where most solutions are gone.
The Problem, Visualized

Standard supplements peak and disappear.
NightWise doesn’t.

Most sleep supplements release everything at bedtime, then fade. NightWise was designed to keep working later in the night.

Fall Asleep Gently helps your body settle into sleep. Standard Peaks early. Wears off. Restore Deeply Sustains support through the middle of the night. Bedtime Middle of the Night Morning
How It Works

Your body doesn’t need support all at once. It needs it at the moments your night is most likely to break.

Three phases. Two releases. One complete system for your night.

NightWise® is built on NightWise’s patented 3-Phase Intelligent Release Technology®, designed to deliver sleep support at bedtime and again hours later, when standard supplements have already worn off.

Phase 1
Immediate Release
Sleep onset support · At bedtime
Paired Calm Support
GABA (gamma-aminobutyric acid) + L-TheanineSelected together to support relaxation and a smooth transition into sleep.*
Circadian Signal
MelatoninSignals the body's natural sleep-wake cycle at bedtime.*
Foundational Sleep Support
MagnesiumSupports relaxation and restful sleep quality.*

Naturally derived ingredients selected to support relaxation and sleep.*

Phase 2
Phase 2: Controlled Hold
Nothing releases for the first 1 to 2 hours. The system holds the second dose, waiting for the point in the night when most sleep products have already worn off. Not a gap. A built-in pause, working while you sleep.
Phase 3
Delayed Release
Sleep maintenance stack · Hours 2–4
Sleep Maintenance Stack
HopsTraditional botanical support for sleep continuity.*
Lemon BalmSupports a calm, relaxed state through the night.*
MagnesiumSustained relaxation to support restful sleep.*
MelatoninSecond delivery designed to extend support beyond standard immediate-release supplements.*

NightWise is built on NightWise’s patented 3-Phase Intelligent Release Technology®, designed to support sleep at both the beginning of the night and hours later.

28 capsules28 doses
1 capsuleper night
Drug-freeNo prescription needed
3 patentsIntelligent Release Technology® delivery system
The Difference

What changes when your sleep holds together

Most products start your night. They don’t carry it through.

Everything Else You've Tried
Immediate release, wears off within 2 hours
No support during the second half of the night
Single formulation for a multi-phase night
Standard melatonin doses cause morning grogginess
Not designed for the 2 AM wake-up
NightWise® Sleep
Phase 1 initiates sleep onset at bedtime
Phase 3 sustains deep restoration hours later
Two distinct formulations timed to the sleep cycle
No morning grogginess
Built specifically for the full night

What this means: your night holds together. And your sleep finally works.

The Product

NightWise® Sleep

A complete three-phase sleep stack for adults with disrupted sleep. Falls asleep, stays asleep, wakes restored. The foundation of the IRT® platform.

28 capsules28 doses
1 capsuleper night
Drug-freeNo prescription needed
3 patentsIntelligent Release Technology® delivery system
See Where to Buy →
Study Validation

Real Sleep. Real Life. Real Results.

NightWise commissioned an independent in-home user testing platform used by leading global consumer brands to run a 7-night study with 100 participants in their own homes, with their real sleep problems.

Most sleep products improve one part of the night. NightWise improves the entire night.

75%
reported improved sleep quality
69%
fell asleep faster
70%
slept longer through the night
69%
fewer nighttime awakenings
62%
woke alert and refreshed

Typical sleep solutions improve onset for ~40–55% of users and rarely support the full night.

Study design: Independent in-home user test · n=100 · 7 nights · Results may vary individually.

Still deciding?

Two minutes. We will guide you to the right NightWise formula.

Not sure NightWise® Sleep is right for you? Answer four questions.

The System, Designed for the Night

One full night. Three distinct moments.
One intelligent system.

Sleep is not one continuous state. It unfolds in phases. NightWise® supports each phase with Intelligent Release Technology®, delivering the right ingredients at the right time across the full night.

Powered by Intelligent Release Technology®
01 PHASE 1 · 0-30 MIN Fall Asleep Gently helps your body settle into sleep. 02 PHASE 2 · 1-2 HRS Stay Asleep Holds support until your sleep is most likely to break. 03 PHASE 3 · HOURS 2-8 Restore Deeply Sustains support through the middle of the night, when recovery matters most. BUILT-IN PAUSE Support is held back until your body needs it most. Bedtime Middle of the Night Morning SLEEP STACK L-Theanine · GABA Magnesium · Melatonin SLEEP STACK Hops · Lemon Balm Magnesium · Melatonin

Precisely timed support across the full night.

Real results. Felt through the night.

What people experience when their sleep finally holds through the night.

I stopped waking up at 3am
I wake up clear, not groggy.
It doesn’t knock me out. It works with my night.
Why It Works

The problem isn’t the ingredients.

It’s the timing.

NightWise uses trusted, clinically studied ingredients. What makes it different is when they’re delivered.

Every Other Product
Built for bedtime. Gone before the night is half over.
A standard sleep supplement delivers everything immediately. It peaks early and fades before the second sleep cycle begins.
NightWise®
Built for the full night.
Phase 1 supports onset at bedtime. Phase 3 delivers again hours later. Two formulations. One system. Timed to how your night actually works.
Intellectual Property

Protected by three issued U.S. patents.

The IRT® platform is the only patented multi-phase bead delivery system in the sleep supplement category.

U.S. Patent 11,351,150
3-Phase Intelligent Release Technology®
U.S. Patent 11,890,271
Phased Multi-Formulation Delivery
U.S. Patent 12,419,860
Multi-Bead Composition Delivery
NightWise® Sleep

The sleep you've been chasing
was never lost at bedtime.
It was lost in the middle of the night.

No sedatives.
No synthetic hormones.
No habit-forming ingredients.

A patented three-phase system
designed to support sleep
from lights out to wake up.

Drug-free.
Available without a prescription.

Find Your Formula 28 capsules · 28 doses · 1 capsule per night · U.S. Patents 11,351,150, 11,890,271 & 12,419,860
Real Sleep. Real Life.
Proprietary Technology

The system behind the sleep.
Built for how the body moves through the night.

Three issued U.S. patents. Independently studied in real-world conditions. A delivery system built around timing, not just ingredients.

Your night doesn’t hold all at once. It unfolds over time.

Most sleep products are built for the beginning of the night. NightWise is built to support what happens after.

NightWise is built on a patented delivery system designed to release support across the full night.

A different way to support sleep. One that stays with you beyond the first hours of the night.

3-Phase Intelligent Release Technology®
Phase 1 Phase 2 Phase 3

A 3-Phase Intelligent Release system. Each phase is released at a different point in the night, helping your sleep hold together from start to finish.

Learn

The Night Shift

What’s happening in your body at night, and why it doesn’t always feel the way it should.

You can fall asleep and still wake up feeling off. You can sleep for hours and still not feel restored.

Night Shift is where we break down what’s actually happening across the night, and why sleep doesn’t always hold the way you expect it to.

Start Here
01

Sedation Is Not Sleep

Some products make you drowsy. That’s not the same as real sleep.

Continue the series
02

Melatonin Starts Sleep. It Does Not Sustain It.

It helps you fall asleep. But it doesn’t support the rest of your night.

5 min read
03

Why Middle-of-the-Night Sleep Is the Real Recovery Window

The most important part of your night is the part most people lose.

6 min read
04

Why Staying Asleep Is Harder Than Falling Asleep

Falling asleep is only the beginning. Holding sleep is where it gets difficult.

6 min read
05

Your Invisible Clock Is Under Pressure

Your internal rhythm is constantly adjusting. When it’s off, your night changes.

7 min read
Women's Health

Menopause and Sleep: Why Your Nights Change

Hormonal shifts don’t just affect how you fall asleep. They change how your night behaves.

8 min read
Men's Health

Waking During the Night: Why It Disrupts More Than You Think

Interruptions don’t just wake you up. They break the structure of your night.

7 min read
Sleep Study

Sleep Study: Real-World Sleep Results

Real-world results from a 7-night in-home study.

View Study →

Editorial Standard NightWise education articles are written by our team and reviewed by independent medical editors before publication. We publish to inform, not to sell. These statements have not been evaluated by the Food and Drug Administration.

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Find NightWise

Available at select retailers.

NightWise® is launching at retail in August 2026. Find the right retailer for you, online and in stores.

Stay Informed

Be the first to know where NightWise® launches next

Early access to availability updates
Retail expansion announcements
Sleep science, clearly explained
NightWise®
🌙
Find Your Formula

Understand where your night breaks.

Answer four quick questions. We’ll map where your night breaks, and match you with the NightWise formula built for that moment.

Your night doesn’t fall apart all at once. We’re identifying exactly where it breaks.

No account needed. About 90 seconds.
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